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dc.contributor.authorBen M'Barek, Marwa
dc.contributor.authorBorgi, Amel
dc.contributor.authorBedhiafi, Walid
dc.contributor.authorBen Hamida, Sana
dc.date.accessioned2019-04-19T14:57:18Z
dc.date.available2019-04-19T14:57:18Z
dc.date.issued2018
dc.identifier.issn1877-0509
dc.identifier.urihttps://basepub.dauphine.fr/handle/123456789/18722
dc.language.isoenen
dc.subjectcommunity detectionen
dc.subjectbiological networksen
dc.subjectGene Ontologyen
dc.subjectGenetic Algorithmen
dc.subjectKyoto Encyclopedia of Genesen
dc.subjectGenomes (KEGG) databaseen
dc.subject.ddc005en
dc.titleGenetic Algorithm for Community Detection in Biological Networksen
dc.typeArticle accepté pour publication ou publié
dc.description.abstractenWe are interested in the detection of communities in biological networks. We focus more precisely on gene interaction networks. They represent protein-protein or gene-gene interactions. A community in such networks corresponds to a set of proteins or genes that collaborate at the same cellular function. Our goal is to identify such network or community from gene annotation sources such as Gene Ontology (GO). In this paper, we propose a Genetic Algorithm (GA) based approach to discover communities in a gene interaction network. Special solution coding and mutation operator are introduced. Otherwise, we propose a specific fitness function based on similarity measure and interaction value between genes. Experiments on real data extracted from the well-known Kyoto Encyclopedia of Genes and Genomes (KEGG) database show the ability of the proposed method to successfully detect existing or even new communities.en
dc.relation.isversionofjnlnameProcedia Computer Science
dc.relation.isversionofjnlvol126en
dc.relation.isversionofjnldate2018
dc.relation.isversionofjnlpages195-204en
dc.relation.isversionofdoi10.1016/j.procs.2018.07.233en
dc.contributor.countryeditoruniversityotherTUNISIA
dc.contributor.countryeditoruniversityotherFRANCE
dc.relation.isversionofjnlpublisherElsevieren
dc.subject.ddclabelProgrammation, logiciels, organisation des donnéesen
dc.relation.forthcomingnonen
dc.relation.forthcomingprintnonen
dc.description.ssrncandidatenonen
dc.description.halcandidateouien
dc.description.readershiprechercheen
dc.description.audienceInternationalen
dc.relation.Isversionofjnlpeerreviewednonen
dc.relation.Isversionofjnlpeerreviewednonen
dc.date.updated2019-03-22T10:19:06Z
hal.person.labIds253759
hal.person.labIds253759
hal.person.labIds247283
hal.person.labIds989
hal.identifierhal-02104847*


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